CAS: 9002‐07‐7 | EC No.: 3.4.21.4
TRYPSIN is highly valued as a workhorse protease across various industries due to its potent digestion of proteins. A naturally occurring pancreatic enzyme, TRYPSIN plays a key role in the human digestive system. TRYPSIN is synthesized by the pancreas as an inactive precursor and, once activated, contributes to protein digestion by cleaving peptide bonds at the carboxyl-terminus of lysine and arginine amino acids. This action breaks proteins down into smaller peptides, a functionality that can be used to effectively mimic the normal digestive processes of the gastrointestinal system.
Trypsin Grades
Medical, Pharmaceutical, and Research
The proteolytic action of TRYPSIN has been put to effective use across broad contexts, being both a mass spectrometry workhorse and meat tenderizer. In the production of vaccines, cells are detached from their vessels using TRYPSIN, cutting cell attachment proteins without harming the cells themselves. This proteolytic action is used in Whey Protein hydrolysis, making amino acids more readily bioavailable for muscle repair and recovery.
Please refer to the tables below for an overview of the application suitability and specifications of our grades of TRYPSIN. Clicking on an individual grade will take you to its product page, where you can learn more.
| Application Suitability | TRYPSIN VI | TRYPSIN IV | TRYPSIN II | TRYPSIN I | TRYPSIN 1:250 | TRYPSIN SE Pancreatin |
|---|---|---|---|---|---|---|
| Vaccine Production | ||||||
| Cell and Tissue Culture | ||||||
| Mass Spectroscopy | ||||||
| Diabetes & Ophthalmic research | ||||||
| USP / EP guideline conformance | ||||||
| Reduce Oedema and Bruising | ||||||
| Enteral Feeding |
Food Processing, Infant Formula & Dietary Supplements
| Application Suitability | TRYPSIN VI | TRYPSIN IV | TRYPSIN II | TRYPSIN I | TRYPSIN 1:250 | TRYPSIN SE Pancreatin |
|---|---|---|---|---|---|---|
| Whey Protein Hydrolysis | ||||||
| Production of Infant Formula | ||||||
| Production of Hypoallergenic Infant Formula | ||||||
| Food Processing | ||||||
| Meat and Seafood Tenderisation | ||||||
| Enhancement of Food Digestibility | ||||||
| Dietary Supplementation | ||||||
| Functional Foods |
USP specifications per Trypsin grade
Please note: This table outlines our experience of the optimal applications per NTI Trypsin grade. This information is not exhaustive of all possible applications, but a starting point from which to select a grade for your use case.
| Specification | TRYPSIN VI | TRYPSIN IV | TRYPSIN II | TRYPSIN I | TRYPSIN 1:250 | TRYPSIN SE Pancreatin |
|---|---|---|---|---|---|---|
| Trypsin U/mg USP | ≥ 2500 | ≥ 250 | ≥ 450 | >2500 | ≥ 250 | / / / |
| Chymotrypsin U/mg USP | ≥ 250 | ≤ 75 | ≤ 75 | ≤ 50 | ≥ 75 | / / / |
| Endotoxin EU/mg | / / / | ≤ 10 | ≤ 10 | / / / | ≤ 10 | / / / |
| Protease U/mg USP | / / / | / / / | / / / | / / / | > 220 | > 250 |
Regulatory:
Regulations may vary by country. Always check the local legislation regarding the usage and claims of this product.
No Warranty: The information contained herein is provided in good faith and, to the best of our knowledge, is true and correct. However, no warranty or guarantee is implied or inferred, and the information may be subject to change without prior notice. Neova Technologies Inc.’s products are sold with the understanding that the purchaser will conduct tests to determine the suitability of these products for their particular use.
Click on the products below to discover more about each of our Trypsin grades:
